2005 archivos - Página 2 de 2 - Histopat laboratoris

A novel logistic model based on clinicopathological features predicts microsatellite instability in colorectal carcinomas

Anna Colomer¹, Nadina Erill¹, August Vidal², Miquel Calvo^3, Ruth Román¹, Montse Verdú^2, Carlos Cordon-Cardo⁴, Xavier Puig ^1,2.

¹BIOPAT, Grup Assistència, Barcelona; ²HISTOPAT Laboratoris, Barcelona; ³Statistics Department of the Universitat de Barcelona, Barcelona and ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York.

High-frequency microsatellite instability has been reported to be associated with good prognosis in colorectal adenocarcinoma. However, methods to assess microsatellite instability (MIN) are based on genetic assays, and are not ideally suited to […]

Alberto 2005-07-23T17:06:28+00:00

Diagnostic sub-classification of non-small cell lung cancer: Importance in clinical therapeutics and prognostication

M. J. Donovan, A. Kotsianti, A. Colomer, M. Verdú, M. Clayton, H. Pang, S. Hamann, C. Cordón-Cardó, X. Puig.

Background: The association of EGFR mutations with bronchoalveolar carcinoma (BAC) / non-small cell lung cancer (NSCLC) and the therapeutic and prognostic variability reported for lung cancer has reinforced the need for more accurate NSCLC sub-classification. The present study utilizes clinical data, immunohistochemistry (IHC), molecular analyses, and quantified immunofluorescent multiplexing (QIFM) to develop a systems pathology model for NSCLC. Methods: 73 NSCLC cases; […]

Alberto 2005-02-09T22:15:16+00:00

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