Correlation between KRAS mutations and clinicopathological features in colorectal carcinomas. A multivariate analysis
Natalia Rodon1, Ruth Roman1, Montse Verdu1,3 ,Miquel Calvo4, Beatriz Garcia-Pelaez1, Marta Gonzalez1, Carme Pubill3 and Xavier Puig1,2,3.
1BIOPAT. Biopatologia Molecular SL, Grup Assistència. 2Hospital de Barcelona-SCIAS, Grup Assistencia. 3Histopat Laboratoris. 4Departament d’Estadística, Facultat de Biologia. UB. Barcelona.
KRAS oncogenic mutations, present in approximately 30-50% of colorectal carcinomas (CRC), result in a lack of response to EGFR inhibitors. The aim of this study was to confirm with a multivariate analysis the correlations observed in our initial univariate approach between KRAS mutational status and […]