Otras publicaciones archivos - Página 6 de 8

A novel logistic model based on clinicopathological features predicts microsatellite instability in colorectal carcinomas

Anna Colomer¹, Nadina Erill¹, August Vidal², Miquel Calvo^3, Ruth Román¹, Montse Verdú^2, Carlos Cordon-Cardo⁴, Xavier Puig ^1,2.

¹BIOPAT, Grup Assistència, Barcelona; ²HISTOPAT Laboratoris, Barcelona; ³Statistics Department of the Universitat de Barcelona, Barcelona and ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York.

High-frequency microsatellite instability has been reported to be associated with good prognosis in colorectal adenocarcinoma. However, methods to assess microsatellite instability (MIN) are based on genetic assays, and are not ideally suited to […]

Alberto 2005-07-23T17:06:28+00:00

Diagnostic sub-classification of non-small cell lung cancer: Importance in clinical therapeutics and prognostication

M. J. Donovan, A. Kotsianti, A. Colomer, M. Verdú, M. Clayton, H. Pang, S. Hamann, C. Cordón-Cardó, X. Puig.

Background: The association of EGFR mutations with bronchoalveolar carcinoma (BAC) / non-small cell lung cancer (NSCLC) and the therapeutic and prognostic variability reported for lung cancer has reinforced the need for more accurate NSCLC sub-classification. The present study utilizes clinical data, immunohistochemistry (IHC), molecular analyses, and quantified immunofluorescent multiplexing (QIFM) to develop a systems pathology model for NSCLC. Methods: 73 NSCLC cases; […]

Alberto 2005-02-09T22:15:16+00:00

Comparison of fluorescence in situ hybridization -FISH- and conventional cytology for early detection of urothelial carcinoma

Nadina Erill ¹, Anna Colomer ^1, Míriam Gorriz ^1,2, Naim Hannaoui ³, Ruth Román ¹, Maria Conangla ², Josep M Banús ³, Carlos Cordon-Cardo ⁴, Xavier Puig ^1,2.

¹BIOPAT, Grup Assistència, Barcelona, Spain; ²HISTOPAT Laboratoris, Barcelona, Spain; ³Institut Català d’Urologia i Nefrologia, ICUN; Barcelona, Spain; and ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA.

Bladder tumors have a high recurrence rate, so treated patients are followed for detection of potential new lesions. Cystoscopy and cytology have been the standard […]

Alberto 2004-07-23T17:48:21+00:00

BRAF mutations in colorectal cancer are linked to loss of hMLH1 expression and proximal location, while independent of K-RAS activation

Anna Colomer ¹, Nadina Erill ^1, August Vidal ², Ruth Román ¹, Montse Verdú ^2, Carlos Cordon-Cardo ³, Xavier Puig ^1,2.

¹BIOPAT, Grup Assistència, Barcelona, Spain; ²HISTOPAT Laboratoris, Barcelona, Spain; ³Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York^.

The RAF gene family encodes RAS-regulated kinases that mediate cellular responses to growth signals. Mutations within the BRAF gene occur in about 10% of colorectal cancers, and are significantly associated to defective mismatch repair (MMR) due […]

Alberto 2004-07-23T17:02:21+00:00

Hibridació in situ Fluorescent -FISH- en la detecció del carcinoma urotelial

N.Erill ^1, A.Colomer ^1, C Pubill ², N. Hannaoui ³, R. Román ^1, M.Conangla², JM. Banús ³, C. Cordón ¹, X. Puig ^1,2.

¹BIOPAT, Grup Assistència; ²HISTOPAT Laboratoris, ³Institut Català d’Urologia i Nefrologia, ICUN; Barcelona.

El carcinoma urotelial de bufeta és un dels tumors malignes més freqüents al nostre entorn. S’associa a una elevada taxa de recurrència, al voltant d’un 80% dels casos, i fins a un 30% pot evolucionar cap a carcinoma invasiu. Actualment, tant el diagnòstic com el seguiment […]

Alberto 2004-06-23T17:46:45+00:00

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