Publicaciones archivos - Página 16 de 20

La inestabilidad de microsatélites en el cáncer colorrectal puede predecirse en base al fenotipo tumoral

A Colomer¹, N Erill¹, A Vidal^1,2, M Calvo³, R Román¹, M Verdú², C Cordón ⁴, X Puig ^1,2.

¹ BIOPAT. Biopatologia Molecular. Grup Assistència. Barcelona. ² Histopat laboratoris, Barcelona. ³Departamento de Estadística de la Universidad de Barcelona. Barcelona. ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York.

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Póster presentado en:

XXII Congreso de la Sociedad Española de Anatomía Patológica 2005

Alberto 2005-09-01T01:12:41+00:00

Molecular protocol for HER2/neu analysis in breast carcinoma

Montse Verdú ^1, Anna Colomer ², Ruth Román ², Nadina Erill ², Miquel Calvo ³, Abelardo Moreno ¹, Carlos Cordon-Cardó ⁴, Xavier Puig ^1,2.

HISTOPAT Laboratoris , Barcelona ^1. BIOPAT, Biopatologia Molecular, Barcelona ^2. Departament d’Estadística de la Universitat de Barcelona, Barcelona ³ y Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA ⁴.

The HER2/neu proto-oncogen is frequently amplified in breast cancer, and serves as a predictive biological determinant to guide trastuzumab therapy. However, consensus has not been reached regarding […]

Alberto 2005-07-23T17:33:20+00:00

A novel multiplexing PCR-based assay of the anaylisis of chromosome 18q status in colorectal cancer

Nadina Erill¹, Anna Colomer¹, Miquel Calvo², August Vidal³, Ruth Román^1, Montse Verdú³, Carlos Cordón-Cardó⁴, Xavier Puig^1,3.

¹BIOPAT, Grup Assistència, Statistics Department, ²Universitat de Barcelona, ³HISTOPAT Laboratoris, Barcelona, and ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York.

Chromosome 18q allelic loss has been reported to have prognostic significance in stage II colorectal carcinoma. We have developed a fluorescent multiplex polymerase chain reaction assay to analyze five microsatellite markers (D18S55, D18S58, D18S61, D18S64 and D18S69) for allelic loss determination at the long […]

Alberto 2005-07-23T17:07:51+00:00

A novel logistic model based on clinicopathological features predicts microsatellite instability in colorectal carcinomas

Anna Colomer¹, Nadina Erill¹, August Vidal², Miquel Calvo^3, Ruth Román¹, Montse Verdú^2, Carlos Cordon-Cardo⁴, Xavier Puig ^1,2.

¹BIOPAT, Grup Assistència, Barcelona; ²HISTOPAT Laboratoris, Barcelona; ³Statistics Department of the Universitat de Barcelona, Barcelona and ⁴Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York.

High-frequency microsatellite instability has been reported to be associated with good prognosis in colorectal adenocarcinoma. However, methods to assess microsatellite instability (MIN) are based on genetic assays, and are not ideally suited to […]

Alberto 2005-07-23T17:06:28+00:00

Diagnostic sub-classification of non-small cell lung cancer: Importance in clinical therapeutics and prognostication

M. J. Donovan, A. Kotsianti, A. Colomer, M. Verdú, M. Clayton, H. Pang, S. Hamann, C. Cordón-Cardó, X. Puig.

Background: The association of EGFR mutations with bronchoalveolar carcinoma (BAC) / non-small cell lung cancer (NSCLC) and the therapeutic and prognostic variability reported for lung cancer has reinforced the need for more accurate NSCLC sub-classification. The present study utilizes clinical data, immunohistochemistry (IHC), molecular analyses, and quantified immunofluorescent multiplexing (QIFM) to develop a systems pathology model for NSCLC. Methods: 73 NSCLC cases; […]

Alberto 2005-02-09T22:15:16+00:00

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